Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.55 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.43 |
| ▸ | OGT | O15294 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179495 | 1.00 | SLC28A1 (0.55) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| Uridine SCHEMBL14335461 | 0.85 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| Uridine SCHEMBL14335474 | 0.85 | SLC28A1 (0.69) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL6141738 | 0.85 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL6141730 | 0.85 | SLC28A1 (0.61) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL6142211 | 0.84 | SLC28A1 (0.55) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL6142216 | 0.84 | SLC28A1 (0.55) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 | |
| SCHEMBL6142111 | 0.83 | LMNA (0.58) | SLC29A1 | |
| SCHEMBL6141694 | 0.83 | LMNA (0.58) | SLC29A1 | |
| SCHEMBL6144408 | 0.82 | SLC28A1 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528640-B1 | Of given formula; can use to inhibit HER2/neu/ ErbB2 gene expression; anticarcinogenic agents | RIBOZYME PHARMACEUTICALS, INCORPORATED | 2003-03-04 | — | — | US | disclosed |
| US-6482932-B1 | Nucleoside triphosphates and their incorporation into oligonucleotides | RIBOZYME PHARMACEUTICALS, INCORPORATED | 2002-11-19 | — | — | US | disclosed |
| US-6127535-A | FOR THE INCORPORATION OF MODIFIED (NON-STANDARD) AND UNMODIFIED NUCLEOTIDES INTO NUCLEIC ACIDS | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-10-03 | — | — | US | disclosed |