⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL27960781 | 0.95 | — | — | |
| SCHEMBL18669978 | 0.76 | — | — | |
| Chloroform SCHEMBL8092701 | 0.74 | — | — | |
| SCHEMBL31572036 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL11874135 | 0.73 | — | — | |
| SCHEMBL289440 | 0.73 | — | — | |
| SCHEMBL28719135 | 0.73 | — | — | |
| SCHEMBL7101873 | 0.73 | — | — | |
| SCHEMBL8177647 | 0.70 | — | — | |
| SCHEMBL2980454 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162883-B2 | Process for the preparation of intermediates useful for making (2S,5R)-7-oxo-n-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | MERCK SHARP & DOHME LLC (US) | 2024-12-10 | — | — | US | claimed |
| CN-111635319-B | Preparation method of compound with nitro-based electron-withdrawing group | 长江师范学院 | 2023-01-24 | — | — | CN | claimed |
| US-20220194941-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR MAKING (2S,5R)-7-OXO-N-PIPERIDIN-4-YL-6-(SULFOXY)-l,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXAMIDE | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | US | claimed |
| CN-114206851-A | Process for the preparation of intermediates useful in the preparation of (2S,5R) -7-oxo-N-piperidin-4-yl-6- (sulfate) -1, 6-diazabicyclo [3.2.1] octane-2-carboxamide | 默沙东公司 | 2022-03-18 | — | — | CN | claimed |
| EP-3959205-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR MAKING (2S,5R)-7-OXO-N-PIPERIDIN-4-YL-6-(SULFOXY)-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXAMIDE | Merck Sharp & Dohme Corp. (US) | 2022-03-02 | — | — | EP | claimed |
| WO-2020219405-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR MAKING (2S,5R)-7-OXO-N-PIPERIDIN-4-YL-6-(SULFOXY)-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXAMIDE | MERCK SHARP & DOHME CORP. (US) | 2020-10-29 | — | — | WO | claimed |
| CN-111635319-A | Compound with nitro-based electron-withdrawing group, non-fullerene electron acceptor material and preparation method thereof | 长江师范学院 | 2020-09-08 | — | — | CN | claimed |
| CN-110283141-A | N- sulphur aryl groups per alkyl group benzoic sulfimide and its preparation method and application | 上海交通大学 | 2019-09-27 | — | — | CN | claimed |
| US-4156058-A | LITHIUM ANODE, ORGANIC SULFOHALOGENIDE SOLVENT | VARTA BATTERIE A.G. (DE) | 1979-05-22 | — | — | US | claimed |
| EP-4646403-A1 | NOVEL CARBOXAMIDE AND SULFONAMIDE PESTICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-12 | — | — | EP | disclosed |
| CN-114206851-B | Process for the preparation of intermediates useful in the preparation of (2S, 5R) -7-oxo-N-piperidin-4-yl-6- (sulfate) -1, 6-diazabicyclo [3.2.1] octane-2-carboxamide | 默沙东有限责任公司 | 2025-02-11 | — | — | CN | disclosed |
| US-12162883-B2 | Process for the preparation of intermediates useful for making (2S,5R)-7-oxo-n-piperidin-4-yl-6-(sulfoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | MERCK SHARP & DOHME LLC (US) | 2024-12-10 | — | — | US | disclosed |
| WO-2024146945-A1 | NOVEL CARBOXAMIDE AND SULFONAMIDE PESTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-11 | — | — | WO | disclosed |
| CN-111635319-B | Preparation method of compound with nitro-based electron-withdrawing group | 长江师范学院 | 2023-01-24 | — | — | CN | disclosed |
| EP-0027906-A1 | Process for preparing sulphon amides | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |
| US-4188483-A | 5-Alkylsulphonyl- and 5-alkenylsulphonylbarbituric acids and derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |
| US-4156058-A | LITHIUM ANODE, ORGANIC SULFOHALOGENIDE SOLVENT | VARTA BATTERIE A.G. (DE) | 1979-05-22 | — | — | US | disclosed |
| US-4060549-A | Process for preparing sulfonic acid fluorides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |
| US-4056622-A | MICROBIOCIDES, FUNGICIDES, BACTERICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-11-01 | — | — | US | disclosed |
| US-RE29032-E | ANTIINFLAMMATORY AGENTS | RIKER LABORATORIES, INC. (US) | 1976-11-09 | — | — | US | disclosed |