Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248947 | 1.00 | ABCG2 (0.33) | ABCG2PTGS1PPARGOPRK1TSHR | |
| SCHEMBL8515105 | 0.86 | TSHR (0.38) | TSHR | |
| SCHEMBL817018 | 0.79 | — | — | |
| SCHEMBL8165020 | 0.75 | TSHR (0.33) | ABCG2PTGS1PPARGOPRK1TSHR | |
| SCHEMBL7216399 | 0.72 | TSHR (0.33) | ABCG2PTGS1PPARGOPRK1TSHR | |
| SCHEMBL7163008 | 0.70 | TSHR (0.35) | TSHR | |
| SCHEMBL56378 | 0.70 | GGPS1 (0.39) | ABCG2PTGS1PPARGOPRK1TSHR | |
| SCHEMBL2120363 | 0.70 | — | — | |
| SCHEMBL4452354 | 0.69 | TSHR (0.37) | PPARGTSHRCYP3A4EP300 | |
| SCHEMBL1539785 | 0.69 | ALDH1A1 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349655-A2 | CATALYST SUPPORT METHOD AND POLYMERIZATION WITH SUPPORTED CATALYSTS | Univation Technologies LLC (US) | 2003-10-08 | — | — | EP | disclosed |
| EP-1339726-A1 | CATALYST COMPOSITION AND METHOD OF POLYMERIZATION | Univation Technologies LLC (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-1242476-A1 | START UP METHODS FOR MULTIPLE CATALYST SYSTEMS | Univation Technologies LLC (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2002046201-A1 | CATALYST COMPOSITION AND METHOD OF POLYMERIZATION | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002045854-A2 | METHOD FOR PREPARING A CATALYST SUPPORT AND POLYMERIZATION WITH SUPPORTED CATALYSTS | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-13 | — | — | WO | disclosed |
| US-20020052453-A1 | Catalyst composition, method of polymerization, and polymer therefrom | LOVEDAY DONALD R (US) | 2002-05-02 | — | — | US | disclosed |
| US-20010034423-A1 | Polymerization catalyst compositions | OSKAM JOHN H (US) | 2001-10-25 | — | — | US | disclosed |
| WO-2001030862-A1 | START UP METHODS FOR MULTIPLE CATALYST SYSTEMS | UNIVATION TECHNOLOGIES, LLC (US) | 2001-05-03 | — | — | WO | disclosed |