SCHEMBL7180195

SCHEMBL7180195

CC(C)O[Hf](Cc1ccccc1)(Cc1ccccc1)C1=CC=CC1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SLC6A2 P23975 2/20 0.30
TAAR1 Q96RJ0 2/20 0.30
MAOA P21397 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
CYP2A6 P11509 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7536548 0.75 TP53 (0.33) TSHR
SCHEMBL8383879 0.75 TP53 (0.33) TSHR
SCHEMBL6055301 0.74 IDO1 (0.32)
Bromide SCHEMBL8384490 0.71 TP53 (0.30)
Hydrochloric Acid SCHEMBL8380512 0.71 KDM4E (0.31)
SCHEMBL16666963 0.69
SCHEMBL27270230 0.64
Hydrochloric Acid SCHEMBL9080054 0.62
Bromide SCHEMBL9079493 0.62
SCHEMBL28149937 0.62 SLC18A2 (0.32) TAAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502683-B2 Catalyst composition for preparation of syndiotactic vinyl aromatic polymers DOW CHEMICAL CO (US) 2003-04-02 EP disclosed
US-5886117-A Process using borane derived catalysts for preparation of syndiotactic vinyl aromatic polymers THE DOW CHEMICAL COMPANY (US) 1999-03-23 US disclosed
CN-1041732-C Process for preparation of syndiotactic vinyl aromatic polymers DOW CHEMICAL CO (US) 1999-01-20 CN disclosed
EP-0742226-B1 Process for preparing borane derived catalysts for preparation of syndiotactic vinyl aromatic polymers DOW CHEMICAL CO (US) 1998-12-02 EP disclosed
EP-0742226-A2 Process for preparing borane derived catalysts for preparation of syndiotactic vinyl aromatic polymers THE DOW CHEMICAL COMPANY (US) 1996-11-13 EP disclosed
EP-0502683-B1 Catalyst composition for preparation of syndiotactic vinyl aromatic polymers DOW CHEMICAL CO (US) 1996-07-17 EP disclosed
EP-0421659-B1 Process for preparation of syndiotactic vinyl aromatic polymers DOW CHEMICAL CO (US) 1996-07-10 EP disclosed
EP-0597961-A4 PROCESS USING BORANE DERIVED CATALYSTS FOR PREPARATION OF SYNDIOTACTIC VINYL AROMATIC POLYMERS. DOW CHEMICAL CO (US) 1995-09-20 EP disclosed
EP-0597961-A1 PROCESS USING BORANE DERIVED CATALYSTS FOR PREPARATION OF SYNDIOTACTIC VINYL AROMATIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1994-05-25 EP disclosed
US-5206197-A CATALYST COMPOSITION FOR PREPARATION OF SYNDIOTACTIC VINYL AROMATIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1993-04-27 US disclosed
WO-1993003067-A1 PROCESS USING BORANE DERIVED CATALYSTS FOR PREPARATION OF SYNDIOTACTIC VINYL AROMATIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1993-02-18 WO disclosed
EP-0502683-A1 Catalyst composition for preparation of syndiotactic vinyl aromatic polymers THE DOW CHEMICAL COMPANY (US) 1992-09-09 EP disclosed
US-5066741-A Contacting monomers with complex catalyst THE DOW CHEMICAL COMPANY (US) 1991-11-19 US disclosed
CN-1050546-A The preparation method of syndiotactic vinyl aromatic polymers DOW CHEMICAL CO (US) 1991-04-10 CN disclosed