SCHEMBL7536548

SCHEMBL7536548

C1=CCC([Hf](Cc2ccccc2)(Cc2ccccc2)C2=CC=CC2)=C1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
CALM1 P0DP23 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8383879 0.85 TP53 (0.33) TP53CALM1ALDH1A1TSHR
SCHEMBL6055301 0.83 IDO1 (0.32) TP53CALM1
Bromide SCHEMBL8384490 0.80 TP53 (0.30) TP53
Hydrochloric Acid SCHEMBL8380512 0.80 KDM4E (0.31) TP53
SCHEMBL7180195 0.75 TSHR (0.32) TSHR
SCHEMBL27270230 0.72
Bromide SCHEMBL9079493 0.70
SCHEMBL28149937 0.70 SLC18A2 (0.32) ALDH1A1
Hydrochloric Acid SCHEMBL9080054 0.70
SCHEMBL8382338 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0294942-B2 Solid catalyst for polymerizing an olefin MITSUI CHEMICALS INC (JP) 2002-05-08 EP claimed
EP-0474391-B1 Polyolefins NIPPON OIL CO LTD (JP) 1995-10-25 EP claimed
EP-0294942-B1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL IND (JP) 1994-07-13 EP claimed
EP-0474391-A2 Polyolefins NIPPON OIL CO. LTD. (JP) 1992-03-11 EP claimed
EP-0812862-B1 Process for polymerizing olefins MITSUI CHEMICALS INC (JP) 2002-11-13 EP disclosed
US-5916982-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1999-06-29 US disclosed
EP-0594218-B1 Process for polymerizing olefins MITSUI CHEMICALS INC (JP) 1999-03-17 EP disclosed
US-5700749-A USING ZIRCONIUM METALLOCENE CATALYST, ALUMOXANE CATALYST, AND ORGANOALUMINUM CATALYST MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-23 US disclosed
EP-0812862-A2 Process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-12-17 EP disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0768319-A1 Process for the production of polyolefins NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0474391-B1 Polyolefins NIPPON OIL CO LTD (JP) 1995-10-25 EP disclosed
EP-0594218-A1 Process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-04-27 EP disclosed
EP-0287666-B1 PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-05-26 EP disclosed
EP-0474391-A2 Polyolefins NIPPON OIL CO. LTD. (JP) 1992-03-11 EP disclosed
EP-0406912-A2 Process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-09 EP disclosed
EP-0287666-A1 PROCESS FOR POLYMERIZING OLEFINS Mitsui Chemicals, Inc. (JP) 1988-10-26 EP disclosed