Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 11/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.36 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875807 | 1.00 | ATR (0.40) | ATRAKT1PIK3C3MTORPIK3CA | |
| SCHEMBL715480 | 0.86 | ATR (0.42) | ATRAKT1PIK3C3MTORPIK3CA | |
| SCHEMBL715481 | 0.86 | ATR (0.42) | ATRAKT1PIK3C3MTORPIK3CA | |
| SCHEMBL717085 | 0.82 | ATR (0.38) | ATRAKT1PIK3C3MTORPIK3CA | |
| SCHEMBL716974 | 0.79 | MTOR (0.44) | ATRPIK3C3MTORPIK3CAPIK3R1 | |
| SCHEMBL716975 | 0.79 | MTOR (0.44) | ATRPIK3C3MTORPIK3CAPIK3R1 | |
| SCHEMBL717084 | 0.77 | ATR (0.39) | ATRAKT1PIK3C3MTORPIK3CA | |
| SCHEMBL713306 | 0.76 | DRD2 (0.38) | PIK3CD | |
| SCHEMBL713305 | 0.76 | DRD2 (0.38) | PIK3CD | |
| SCHEMBL717198 | 0.75 | ADORA2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | claimed |
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | disclosed |
| US-8785628-B2 | Triazine derivatives as kinase inhibitors | UCB PHARMA, S.A. (BE) | 2014-07-22 | — | — | US | disclosed |
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | UCB PHARMA, S.A. (BE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053167-A1 | Triazine Derivatives as Kinase Inhibitors | MAP3K15, PI4KA, MAP3K20 | ATR 368/4885AKT1 297/4885PIK3C3 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.