Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7182447 | 0.96 | KDM4E (0.42) | KDM4EMMP12SMN1; SMN2KCNN4LMNA | |
| Hydrochloric Acid SCHEMBL7179476 | 0.96 | KDM4E (0.42) | KDM4EMMP12SMN1; SMN2KCNN4LMNA | |
| Hydrochloric Acid SCHEMBL7177836 | 0.96 | KDM4E (0.42) | KDM4EMMP12SMN1; SMN2KCNN4LMNA | |
| Hydrochloric Acid SCHEMBL7174198 | 0.96 | KDM4E (0.42) | KDM4EMMP12SMN1; SMN2KCNN4LMNA | |
| Hydrochloric Acid SCHEMBL7178835 | 0.96 | KDM4E (0.42) | KDM4EMMP12SMN1; SMN2KCNN4LMNA | |
| Hydrochloric Acid SCHEMBL7174822 | 0.96 | KDM4E (0.42) | KDM4EMMP12SMN1; SMN2KCNN4LMNA | |
| SCHEMBL915419 | 0.96 | KDM4E (0.44) | KDM4EMMP12SMN1; SMN2KCNN4LMNA | |
| SCHEMBL20410988 | 0.89 | KDM4E (0.40) | KDM4EMMP12SMN1; SMN2KCNN4TDP1 | |
| SCHEMBL20410870 | 0.87 | KDM4E (0.39) | KDM4EMMP12SMN1; SMN2KCNN4MEN1 | |
| SCHEMBL12075532 | 0.86 | KDM4E (0.58) | KDM4EMMP12SMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |