Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 9/20 | 0.45 |
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185757 | 0.99 | THRB (0.47) | ITGB1ITGA4THRBTHRAPLA2G2A | |
| SCHEMBL7177697 | 0.96 | ITGB1 (0.44) | ITGB1ITGA4THRBTHRAPLA2G2A | |
| SCHEMBL7174748 | 0.92 | ELANE (0.38) | ITGB1ITGA4THRBTHRAELANE | |
| SCHEMBL7182727 | 0.89 | THRB (0.43) | ITGB1ITGA4THRBTHRAPLA2G2A | |
| SCHEMBL7175321 | 0.89 | THRB (0.42) | THRBTHRAPLA2G2A | |
| SCHEMBL7186955 | 0.88 | THRB (0.45) | ITGB1ITGA4THRBTHRAPLA2G2A | |
| SCHEMBL7184676 | 0.88 | THRB (0.44) | THRBTHRAPLA2G2ATP53TSHR | |
| SCHEMBL7185554 | 0.88 | THRB (0.44) | ITGB1ITGA4THRBTHRAPLA2G2A | |
| SCHEMBL7175225 | 0.87 | THRB (0.46) | ITGB1ITGA4THRBTHRAPLA2G2A | |
| SCHEMBL7175015 | 0.86 | FFAR1 (0.35) | ITGB1ITGA4THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579663-B2 | Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-17 | — | — | US | disclosed |
| US-20020107413-A1 | Organometallic monoacylarylphosphines | WOLF JEAN-PIERRE (CH) | 2002-08-08 | — | — | US | disclosed |
| US-6399805-B2 | SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-04 | — | — | US | disclosed |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | CIBA SPECIALTY CHEMICALS CORP. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107413-A1 | Organometallic monoacylarylphosphines | CBR1, NAF1, DHCR24 | ITGB1 2786/4885ITGA4 3521/4885THRB 2119/4885 |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | NAF1, DHCR24, CBR1 | ITGB1 3321/4885ITGA4 3643/4885THRB 2521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.