SCHEMBL7180731

SCHEMBL7180731

CCCCCCOc1ccc(PC(=O)c2c(OC)cccc2OC)cc1.[LiH]

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.48
PPARA Q07869 1/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
PLA2G4B P0C869 4/20 0.46
RARB P10826 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7187489 0.99 NR5A1 (0.46) NR5A1PPARATP53TSHRPLA2G4B
SCHEMBL7187607 0.96 SMN1; SMN2 (0.46) PPARA
SCHEMBL7189280 0.93 MAPT (0.45) NR5A1PPARATP53TSHRPLA2G4B
SCHEMBL7182674 0.92 MAPT (0.46) NR5A1PPARATP53TSHRPLA2G4B
SCHEMBL7183431 0.91 SMN1; SMN2 (0.46)
SCHEMBL7181016 0.89 L3MBTL1 (0.45) PPARA
SCHEMBL7187543 0.89 PLA2G4B (0.47) NR5A1TP53TSHRPLA2G4BRARB
SCHEMBL7181380 0.88 PLA2G4B (0.46) NR5A1TP53TSHRPLA2G4BRARB
SCHEMBL7187424 0.86 MAPT (0.46) TP53
SCHEMBL7183274 0.86 SMN1; SMN2 (0.58) TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 NR5A1 49/4885PPARA 3039/4885TP53 3575/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 NR5A1 133/4885PPARA 2624/4885TP53 3524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.