Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7179008 | 0.85 | DAO (0.36) | LMNAALDH1A1CYP1A2TSHRHRH4 | |
| SCHEMBL9867255 | 0.85 | ALDH1A1 (0.37) | LMNAALDH1A1CYP1A2TSHRMAPK1 | |
| SCHEMBL9876539 | 0.84 | CYP1A2 (0.38) | LMNAALDH1A1CYP1A2DAOHTT | |
| SCHEMBL9865982 | 0.84 | NPC1 (0.44) | LMNAALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL9866779 | 0.84 | CYP1A2 (0.41) | LMNAALDH1A1CYP1A2MAPK1HTT | |
| SCHEMBL7174490 | 0.84 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL9866225 | 0.83 | PSMB5 (0.46) | — | |
| SCHEMBL7175108 | 0.83 | SLC47A1 (0.31) | ALDH1A1 | |
| SCHEMBL8581367 | 0.83 | SLC47A1 (0.31) | — | |
| SCHEMBL9866272 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655914-B1 | Use of Histamine-2 agonists for treatment of sexual dysfunction | NAHOUM CESAR ROBERTO DIAS (BR) | 2003-02-26 | — | — | EP | disclosed |
| EP-0655914-A4 | NOVEL COMPOSITIONS. | NAHOUM CESAR ROBERTO DIAS (BR) | 1998-04-22 | — | — | EP | disclosed |
| EP-0655914-A1 | NOVEL COMPOSITIONS | NAHOUM, Cesar Roberto Dias (BR) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994004120-A2 | METHODS OF TREATING SEXUAL DYSFUNCTION IN ANIMALS WITH AND H AGONIST | NAHOUM CESAR ROBERTO DIAS (BR) | 1994-03-03 | — | — | WO | disclosed |
| US-4013659-A | CERTAIN N,N'-DISUBSTITUTED GUANIDINE COMPOUNDS AND THEIR USE | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |