SCHEMBL7180894

SCHEMBL7180894

FCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10618503 1.00 LMNA (0.43) LMNATHRB
SCHEMBL5350698 1.00 LMNA (0.43) LMNATHRB
SCHEMBL5684922 0.97 LMNA (0.38) LMNA
SCHEMBL15403544 0.88 LMNA (0.33) LMNA
SCHEMBL7643011 0.84 LMNA (0.42) LMNATHRB
SCHEMBL7641162 0.84 LMNA (0.42) LMNATHRB
SCHEMBL30059624 0.83 LMNA (0.33) LMNA
SCHEMBL3058414 0.81 LMNA (0.37) LMNATHRB
SCHEMBL810661 0.80 LMNA (0.35) LMNA
SCHEMBL3770995 0.80 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114516781-B Preparation method of perfluorooctyl ethyl iodide and perfluorooctyl ethylene 山东大学 2023-09-19 CN disclosed
US-11491244-B2 Labeled fluorocarbon agents for positron emission tomography imaging Sunnybrook Research Institute (CA) 2022-11-08 US disclosed
CN-114516781-A Preparation method of perfluorooctyl ethyl iodide and perfluorooctyl ethylene 山东大学 2022-05-20 CN disclosed
EP-1049659-B1 FLUORINATED OXYVINYL COMPOUNDS AND METHODS OF PREPARING AND USING SAME ALLIED SIGNAL INC (US) 2003-07-23 EP disclosed
EP-1049659-A1 FLUORINATED OXYVINYL COMPOUNDS AND METHODS OF PREPARING AND USING SAME AlliedSignal Inc. (US) 2000-11-08 EP disclosed
US-6133472-A OXYVINYL GROUPS SEPARATED FROM FLUORINE CONTAINING GROUPS BY AT LEAST ONE ALKYLENE GROUP HAVING 2-8 CARBON ATOMS AND BY AT LEAST ONE OXYGEN ATOM IN ADDITION TO THE OXYGEN ON THE OXYVINYL; READILY RADIATION CURABLE ALLIEDSIGNAL INC. (US) 2000-10-17 US disclosed
WO-1999036381-A1 FLUORINATED OXYVINYL COMPOUNDS AND METHODS OF PREPARING AND USING SAME ALLIEDSIGNAL INC. (US) 1999-07-22 WO disclosed