SCHEMBL718092

SCHEMBL718092

Cc1ccc(N2C(=O)CCCC2=O)c(C)c1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.62
TP53 P04637 1/20 0.62
GAA P10253 1/20 0.51
KMT2A Q03164 6/20 0.51
LMNA P02545 2/20 0.51
MEN1 O00255 4/20 0.49
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 5/20 0.48
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPT P10636 4/20 0.44
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
CASP6 P55212 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MCOLN3 Q8TDD5 1/20 0.43
KDM4E B2RXH2 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17059034 0.85 GAA (0.64) HPGDTP53GAAKMT2ALMNA
SCHEMBL6140971 0.82 TP53 (0.59) HPGDTP53GAAKMT2ALMNA
SCHEMBL2760313 0.79 HSD17B10 (0.57) TP53GAAKMT2ALMNAMEN1
SCHEMBL8305499 0.77 HSD17B10 (0.51) HPGDTP53GAAKMT2ALMNA
SCHEMBL719077 0.77 SMN1; SMN2 (0.62) HPGDTP53GAAKMT2ALMNA
SCHEMBL17059036 0.77 HSD17B10 (0.63) HPGDTP53GAAKMT2ALMNA
SCHEMBL19046765 0.77 TP53 (1.00) HPGDTP53GAAKMT2ALMNA
SCHEMBL29485049 0.75 MGLL (0.59) HPGDTP53KMT2AMEN1NPSR1
SCHEMBL717739 0.75 MGLL (0.59) HPGDTP53KMT2AMEN1NPSR1
SCHEMBL10278492 0.74 TP53 (0.53) HPGDTP53GAAKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed