SCHEMBL7180925

SCHEMBL7180925

Cc1cc(OCc2ccccc2)ccc1PC(=O)c1c(C)cccc1C.[LiH]

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.50
FFAR1 O14842 10/20 0.48
FFAR4 Q5NUL3 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
MRGPRX4 Q96LA9 1/20 0.46
NR4A2 P43354 1/20 0.46
S1PR1 P21453 1/20 0.45
S1PR5 Q9H228 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179941 0.92 MRGPRX4 (0.50) MAOBFFAR1CASP3SENP8SENP7
SCHEMBL7188915 0.92 MAOB (0.48) MAOBFFAR1FFAR4CASP3SENP8
SCHEMBL7179313 0.91 MRGPRX4 (0.53) MAOBFFAR1CASP3SENP8SENP7
SCHEMBL7177769 0.91 MAOB (0.48) MAOBFFAR1FFAR4CASP3SENP8
SCHEMBL7188222 0.89 NR4A2 (0.47) MAOBFFAR1CASP3SENP8SENP7
SCHEMBL7185200 0.89 L3MBTL1 (0.48) MAOBFFAR1CASP3SENP8SENP7
Lithium SCHEMBL7177776 0.88 MAOB (0.48) MAOBFFAR1FFAR4CASP3SENP8
SCHEMBL7182561 0.87 MAOB (0.46) MAOBFFAR1FFAR4CASP3SENP8
SCHEMBL7177524 0.87 MRGPRX4 (0.45) MAOBFFAR1CASP3SENP8SENP7
SCHEMBL7179771 0.85 L3MBTL1 (0.45) MAOBFFAR1CASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 MAOB 4189/4885FFAR1 671/4885FFAR4 1611/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 MAOB 4319/4885FFAR1 711/4885FFAR4 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.