SCHEMBL718093

SCHEMBL718093

Cc1cccc(N2C(=O)CCCC2=O)c1C

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
GAA P10253 1/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
LMNA P02545 2/20 0.44
TSHR P16473 2/20 0.44
HTT P42858 1/20 0.44
ADRB1 P08588 1/20 0.43
ALDH1A1 P00352 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
MGLL Q99685 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL719077 0.85 SMN1; SMN2 (0.62) MAPTSMN1; SMN2GAAMEN1KMT2A
SCHEMBL4809461 0.79 MEN1 (0.57) MAPTSMN1; SMN2MEN1KMT2AHPGD
SCHEMBL6025147 0.76 KMT2A (0.66) MAPTSMN1; SMN2GAAMEN1KMT2A
SCHEMBL710771 0.75 MGLL (0.70) TSHRADRB1ALDH1A1NPSR1MAPK1
SCHEMBL29440938 0.75 MGLL (0.70) TSHRADRB1ALDH1A1NPSR1MAPK1
SCHEMBL8747045 0.74 HPGD (0.49) MAPTSMN1; SMN2GAAMEN1KMT2A
SCHEMBL14867320 0.73 NOTUM (0.46) MAPTSMN1; SMN2GAAMEN1KMT2A
SCHEMBL30758617 0.72 KMT2A (0.62) MEN1KMT2ALMNAALDH1A1MGLL
SCHEMBL11610945 0.72 KDM5A (0.59) MAPTGAAMEN1KMT2AHPGD
SCHEMBL29168855 0.72 KMT2A (0.62) MEN1KMT2ALMNAALDH1A1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed