Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BID | P55957 | 3/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.31 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7175801 | 0.97 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7171152 | 0.97 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7177087 | 0.97 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7176130 | 0.97 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7181600 | 0.97 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7178593 | 0.97 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7177513 | 0.91 | GRM5 (0.35) | — | |
| Hydrochloric Acid SCHEMBL7179236 | 0.89 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7176690 | 0.89 | TLR8 (0.34) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 | |
| Hydrochloric Acid SCHEMBL7180794 | 0.89 | TLR8 (0.34) | CYP3A4CYP2D6CYP2C9KCNH2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |