SCHEMBL7181552

SCHEMBL7181552

CC(C)(C)c1ccc2c(c1)Cc1c-2ccc(C(C)(C)C)c1[Hf]

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL540564 0.98 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL6672082 0.88 NPC1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL30028170 0.83 ALDH1A1 (0.34) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL18261224 0.83 ALDH1A1 (0.34) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL6003856 0.81 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1538380 0.81 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL7719173 0.81 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL27862673 0.81 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Hydrochloric Acid SCHEMBL5086023 0.80 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Hydrochloric Acid SCHEMBL540421 0.80 ALDH1A1 (0.33) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3827033-B1 PREPARATION OF BIMODAL RUBBER, THERMOPLASTIC VULCANIZATES, AND ARTICLES MADE THEREFROM EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-01 EP claimed
US-11466149-B2 Preparation of bimodal rubber, thermoplastic vulcanizates, and articles made therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-10-11 US claimed
CN-114539477-A Preparation method of ethylene propylene diene monomer 浙江大学衢州研究院 2022-05-27 CN claimed
CN-114539478-A Preparation method of comb-shaped polyolefin thermoplastic elastomer based on feeding strategy regulation and control 浙江大学衢州研究院 2022-05-27 CN claimed
EP-3827033-B1 PREPARATION OF BIMODAL RUBBER, THERMOPLASTIC VULCANIZATES, AND ARTICLES MADE THEREFROM EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-01 EP disclosed
CN-114437261-B Olefin polymerization metallocene catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-113906059-B Catalyst system 博里利斯股份公司 2024-03-12 CN disclosed
CN-116234871-A Apparatus and method for producing in-line mixed polymers 博里利斯股份公司 2023-06-06 CN disclosed
CN-116209688-A Ethylene copolymers with improved melting and glass transition temperatures 博里利斯股份公司 2023-06-02 CN disclosed
CN-116209687-A Ethylene copolymers with improved melting and glass transition temperatures 博里利斯股份公司 2023-06-02 CN disclosed
CN-116194494-A Ethylene-octene copolymer with improved performance characteristics 博里利斯股份公司 2023-05-30 CN disclosed
US-11466149-B2 Preparation of bimodal rubber, thermoplastic vulcanizates, and articles made therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-10-11 US disclosed
CN-111194327-B Means to increase molecular weight and decrease density of ethylene interpolymers using homogeneous and heterogeneous catalyst formulations 诺瓦化学品(国际)股份有限公司 2022-10-11 CN disclosed
CN-114539478-A Preparation method of comb-shaped polyolefin thermoplastic elastomer based on feeding strategy regulation and control 浙江大学衢州研究院 2022-05-27 CN disclosed
CN-114539477-A Preparation method of ethylene propylene diene monomer 浙江大学衢州研究院 2022-05-27 CN disclosed
CN-111194327-A Means to increase the molecular weight and decrease the density of ethylene interpolymers using homogeneous and heterogeneous catalyst formulations 诺瓦化学品(国际)股份有限公司 2020-05-22 CN disclosed
CN-106068291-B Olefin-based resin, its manufacturing method and propylene resin composition 三井化学株式会社 2019-03-12 CN disclosed
CN-109196039-A Composition for thermoplastic elastomer, its manufacturing method and formed body 三井化学株式会社 2019-01-11 CN disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed