Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417298 | 0.87 | TDP1 (0.53) | TDP1CYP3A4ESR1ESR2GAA | |
| Tetramethylammonium Ion SCHEMBL7635160 | 0.85 | TDP1 (0.46) | TDP1CYP3A4ESR1ESR2GAA | |
| SCHEMBL6901291 | 0.79 | TDP1 (0.50) | TDP1CYP3A4ESR1ESR2GAA | |
| SCHEMBL7197098 | 0.78 | DNM1 (0.40) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27658523 | 0.76 | CYP3A4 (0.42) | TDP1CYP3A4ESR1ESR2GAA | |
| Phenol SCHEMBL9616945 | 0.69 | TDP1 (0.39) | TDP1CYP3A4GABRA1GABRB2LMNA | |
| Methyl Alcohol SCHEMBL16974123 | 0.69 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2GAA | |
| SCHEMBL31544056 | 0.69 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2GAA | |
| SCHEMBL27570561 | 0.69 | TDP1 (0.80) | TDP1CYP3A4ESR1ESR2GAA | |
| SCHEMBL21084304 | 0.69 | TDP1 (0.67) | TDP1CYP3A4ESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275694-A1 | AROMATIC POLYCARBONATE COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF | TEIJIN LIMITED (JP) | 2003-01-15 | — | — | EP | disclosed |