SCHEMBL7181908

SCHEMBL7181908

Nc1cccc(Oc2cc(N)cc(Cl)c2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.62
ALDH1A1 P00352 5/20 0.54
MAPT P10636 3/20 0.50
ATM Q13315 1/20 0.50
POLB P06746 1/20 0.50
HSP90AA1 P07900 1/20 0.50
CYP3A4 P08684 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MITF O75030 1/20 0.48
GAA P10253 1/20 0.48
GFER P55789 1/20 0.48
NLRP1 Q9C000 1/20 0.48
NOD2 Q9HC29 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
NLRP3 Q96P20 1/20 0.47
TP53 P04637 2/20 0.44
TERT O14746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7190143 0.94 MAOB (0.64) MAOBALDH1A1MAPTATMPOLB
Hydrochloric Acid SCHEMBL10631813 0.92 MAOB (0.62) MAOBALDH1A1MAPTATMPOLB
SCHEMBL633481 0.88 MAOB (0.67) MAOBALDH1A1MAPTATMPOLB
SCHEMBL3791201 0.86 MEN1 (0.63) MAOBALDH1A1MAPTPOLBCYP3A4
SCHEMBL2444031 0.86 MAOB (0.75) MAOBALDH1A1MAPTATMPOLB
SCHEMBL7190886 0.85 CYP3A4 (0.60) MAOBALDH1A1MAPTCYP3A4MEN1
SCHEMBL2440288 0.83 MAOB (0.78) MAOBALDH1A1MAPTATMPOLB
SCHEMBL29520683 0.83 MAOB (0.78) MAOBALDH1A1MAPTATMPOLB
SCHEMBL55303 0.83 MAOB (0.86) MAOBALDH1A1MAPTATMPOLB
SCHEMBL29414092 0.83 MAOB (0.86) MAOBALDH1A1MAPTATMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed