Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433360 | 0.89 | MAOA (0.65) | CYP3A4TP53MAOBMAOAMEN1 | |
| SCHEMBL7188917 | 0.89 | MAOA (0.65) | CYP3A4TP53MAOBMAOAMEN1 | |
| SCHEMBL3791201 | 0.87 | MEN1 (0.63) | CYP3A4TP53MAOBMAOAMEN1 | |
| SCHEMBL7181908 | 0.85 | MAOB (0.62) | CYP3A4TP53MAOBMAOAMEN1 | |
| SCHEMBL2182610 | 0.84 | GRM5 (0.43) | CYP3A4TP53 | |
| SCHEMBL2960969 | 0.84 | MEN1 (0.52) | CYP3A4TP53MAOBMAOAMEN1 | |
| SCHEMBL7190411 | 0.82 | CYP3A4 (0.45) | CYP3A4TP53MAOBMAOAMEN1 | |
| SCHEMBL29371018 | 0.80 | CYP3A4 (0.55) | CYP3A4TP53NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL291988 | 0.80 | CYP3A4 (0.55) | CYP3A4TP53NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10706723 | 0.80 | TSHR (0.57) | CYP3A4TP53MAOBMAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |