SCHEMBL7182080

SCHEMBL7182080

CC12C(=O)OC(=O)C1(C)C1C=CC2C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.48
CYP3A4 P08684 3/20 0.48
MAPK1 P28482 3/20 0.48
HIF1A Q16665 2/20 0.48
LMNA P02545 2/20 0.48
CYP1A2 P05177 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
NFKB1 P19838 1/20 0.48
THPO P40225 1/20 0.48
PPM1B O75688 1/20 0.48
PTPN1 P18031 1/20 0.48
PPP1CC P36873 1/20 0.48
TFPI2 P48307 1/20 0.48
PPP5C P53041 1/20 0.48
PPP2CA P67775 1/20 0.48
PPP1CA P62136 1/20 0.48
KDM4E B2RXH2 1/20 0.48
GMNN O75496 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14325606 0.86 TP53 (0.54) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL11569562 0.82 TP53 (0.38) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL10477952 0.76 TP53 (0.32) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL7109066 0.74 TSHR (0.31) TSHR
SCHEMBL14315040 0.74
SCHEMBL7187721 0.73 TP53 (0.34) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL11573985 0.73 TP53 (0.30) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL16192645 0.73 TP53 (0.30) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL17698446 0.73 TP53 (0.30) TP53CYP3A4MAPK1HIF1ALMNA
SCHEMBL7190956 0.72 CYP2D6 (0.32) TP53CYP3A4MAPK1HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US claimed
EP-4617314-A1 COMPOSITION FOR FORMING A MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS, METHOD FOR FORMING A MOLDED PRODUCT, AND MOLDED PRODUCT HAVING LOW DIELECTRIC LOSS Daikin Industries, Ltd. (JP) 2025-09-17 EP disclosed
US-10329383-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2019-06-25 US disclosed
US-20190112406-A1 Resins and Radomes Including Them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2019-04-18 US disclosed
US-20180258223-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2018-09-13 US disclosed
WO-2018151800-A2 RADOME FABRICATION USING CYCLIC OLEFIN RESIN IN LIQUID MOLDING SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-08-23 WO disclosed
US-9914803-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-03-13 US disclosed
US-9823563-B2 Alcohol compound and method for producing same, method for producing lactone compound, (meth)acrylate ester and method for producing same, polymer and method for producing same, and resist composition and method for producing substrate using same MITSUBISHI CHEMICAL CORPORATION (JP) 2017-11-21 US disclosed
US-9823563-B2 Alcohol compound and method for producing same, method for producing lactone compound, (meth)acrylate ester and method for producing same, polymer and method for producing same, and resist composition and method for producing substrate using same MITSUBISHI CHEMICAL CORPORATION (JP) 2017-11-21 US disclosed
EP-3013869-A1 RESINS AND RADOMES INCLUDING THEM Saint-gobain Performance Plastics Corporation (US) 2016-05-04 EP disclosed
US-5164469-A Substrate for optical disks, ring opening polymerization of tetracyclododecene derivatives JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-11-17 US disclosed
US-5053471-A Methathesis ring opening polymerization of polar substituted norbornenes or octahydromethanonphthalenes; optics JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-10-01 US disclosed
EP-0409291-A2 Thermoplastic resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-23 EP disclosed
EP-0317262-A2 Transparent resin material JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-05-24 EP disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed
US-4176220-A COORDINATION CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-11-27 US disclosed
US-4106943-A RING-OPENED POLYMER OR COPOLYMER OF NORBORNENE DERIVATIVE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1978-08-15 US disclosed
US-4068063-A Catalyst composition for ring-opening polymerization of norbornene derivatives and process for polymerizing same JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1978-01-10 US disclosed
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US disclosed
US-4011386-A RING OPENING, POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-03-08 US disclosed