SCHEMBL7109066

SCHEMBL7109066

CC12C(=O)NC(=O)C1(C)C1C=CC2C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182080 0.74 TP53 (0.48) TSHR
SCHEMBL23277693 0.72
SCHEMBL15695055 0.70 ALDH1A1 (0.40) TSHRNPSR1
SCHEMBL11569562 0.68 TP53 (0.38) TSHR
SCHEMBL14315040 0.67
SCHEMBL11781834 0.67
SCHEMBL11736081 0.64
SCHEMBL21000266 0.63 HSD11B1 (0.34) TSHRNPSR1
SCHEMBL20626709 0.63 HSD11B1 (0.34) TSHRNPSR1
SCHEMBL17503523 0.62 CYP2D6 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113027-B1 Olefin copolymer having functional group, production process thereof and rubber composition JSR CORP (JP) 2003-10-15 EP disclosed
US-6534586-B2 Mechanical properties; having nonhalogenated flame retardant JSR CORPORATION (JP) 2003-03-18 US disclosed
US-6403742-B2 RUBBER JSR CORPORATION (JP) 2002-06-11 US disclosed
US-20020058746-A1 Flame-retardant rubber composition and flame-retardant elastomer JSR CORPORATION (JP) 2002-05-16 US disclosed
EP-1191061-A1 Flame-retardant rubber composition and flame-retardant elastomer JSR Corporation (JP) 2002-03-27 EP disclosed
EP-1113027-A1 Olefin copolymer having functional group, production process thereof and rubber composition JSR Corporation (JP) 2001-07-04 EP disclosed
EP-0544304-B1 Catalyst composition for hydrogenating olefinically unsaturated polymers JAPAN SYNTHETIC RUBBER CO LTD (JP) 1998-02-04 EP disclosed
EP-0434469-B1 Hydrogenation catalyst composition and process for hydrogenating olefinically unsaturated polymer using the same JAPAN SYNTHETIC RUBBER CO LTD (JP) 1995-02-22 EP disclosed
US-5270274-A Catalyst composition for hydrogenating olefinically unsaturated polymers JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-12-14 US disclosed
EP-0544304-A1 Catalyst composition for hydrogenating olefinically unsaturated polymers JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-06-02 EP disclosed
US-5169905-A Using a bis(cyclopentadienyl)transition metal compound and an alkali aluminum organic complex as catalyst JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-08 US disclosed
EP-0339986-B1 NOVEL CATALYST FOR HYDROGENATION OF POLYMER AND PROCESS FOR HYDROGENATING POLYMER WITH THE CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-02 EP disclosed
EP-0434469-A2 Hydrogenation catalyst composition and process for hydrogenating olefinically unsaturated polymer using the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-06-26 EP disclosed