SCHEMBL7182409

SCHEMBL7182409

Oc1ccc(Cc2ccc(O)c(C3CCCCC3)c2)cc1C1CCCCC1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.71
BACE1 P56817 1/20 0.71
HSP90AA1 P07900 1/20 0.53
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
THRB P10828 3/20 0.45
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
THRA P10827 2/20 0.41
ACMSD Q8TDX5 2/20 0.40
IDH1 O75874 1/20 0.40
MEN1 O00255 2/20 0.39
GAA P10253 2/20 0.39
KMT2A Q03164 2/20 0.39
KLKB1 P03952 1/20 0.39
CTSB P07858 1/20 0.39
MMP9 P14780 1/20 0.39
DNMT1 P26358 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27936312 0.93 NUDT1 (0.63) NUDT1BACE1HSP90AA1CA1CA2
SCHEMBL22103820 0.92 NUDT1 (0.61) NUDT1BACE1HSP90AA1CA1CA2
SCHEMBL28171805 0.91 ESR1 (0.61) NUDT1BACE1HSP90AA1CA1CA2
SCHEMBL27602507 0.89 NUDT1 (0.58) NUDT1BACE1HSP90AA1THRBESR1
SCHEMBL10597858 0.89 BACE1 (0.81) NUDT1BACE1HSP90AA1THRBTHRA
SCHEMBL27749308 0.87 NUDT1 (0.69) NUDT1BACE1HSP90AA1THRBTHRA
SCHEMBL3270518 0.86 NUDT1 (0.58) NUDT1BACE1HSP90AA1CA1CA2
SCHEMBL10596917 0.86 NUDT1 (0.77) NUDT1BACE1HSP90AA1THRBTHRA
SCHEMBL13586652 0.86 NUDT1 (0.67) NUDT1BACE1HSP90AA1THRBTHRA
SCHEMBL10595253 0.86 NUDT1 (0.77) NUDT1BACE1HSP90AA1THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9703215-B2 Electrophotographic photoreceptor, method of producing same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2017-07-11 US disclosed
US-9703215-B2 Electrophotographic photoreceptor, method of producing same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2017-07-11 US disclosed
US-20160161870-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2016-06-09 US disclosed
US-20160161870-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2016-06-09 US disclosed
US-20030224222-A1 Aromatic polysulfone resin and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-12-04 US disclosed
EP-0329991-A1 Aromatic polycarbonate film IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-08-30 EP disclosed
US-4012554-A Single coating record system-solvent loss produces color NCR CORPORATION (US) 1977-03-15 US disclosed