Acetophenone

Acetophenone

SCHEMBL7182513

CC(=O)c1ccccc1.CC(C)(O)C(C)(C)O.COC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.52
MAPT P10636 3/20 0.52
SRC P12931 1/20 0.48
TSHR P16473 2/20 0.48
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
LMNA P02545 2/20 0.47
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CES1 P23141 3/20 0.45
CES2 O00748 2/20 0.45
MAOB P27338 2/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NPSR1 Q6W5P4 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL2875026 0.94 SMN1; SMN2 (0.58) SMN1; SMN2MAPTSRCTSHRALDH1A1
Acetophenone SCHEMBL11307226 0.90 SMN1; SMN2 (0.50) SMN1; SMN2MAPTSRCTSHRALDH1A1
Acetophenone SCHEMBL27464172 0.89 MAPT (0.62) SMN1; SMN2MAPTTSHRALDH1A1HPGD
Acetophenone SCHEMBL11149997 0.88 TSHR (0.58) SMN1; SMN2MAPTTSHRALDH1A1HPGD
Acetophenone SCHEMBL27976272 0.88 SMN1; SMN2 (0.52) SMN1; SMN2MAPTSRCTSHRALDH1A1
Acetophenone SCHEMBL11354339 0.85 LMNA (0.46) SMN1; SMN2MAPTSRCTSHRALDH1A1
Acetophenone SCHEMBL7182516 0.83 SMN1; SMN2 (0.52) SMN1; SMN2MAPTSRCTSHRALDH1A1
Acetophenone SCHEMBL28462506 0.82 MAPT (0.60) SMN1; SMN2MAPTTSHRALDH1A1HPGD
Acetophenone SCHEMBL28462505 0.82 MAPT (0.60) SMN1; SMN2MAPTTSHRALDH1A1HPGD
Acetophenone SCHEMBL11157652 0.82 LMNA (0.50) SMN1; SMN2MAPTTSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002764-B1 PROCESS FOR THE PREPARATION OF POLYETHYLENES BAYER AG (DE) 1981-03-25 EP claimed
US-4220742-A Process for the polymerization of ethylene in the presence of diaryl glycol ethers BAYER AKTIENGESELLSCHAFT (DE) 1980-09-02 US claimed
CN-108026248-B Thermosetting epoxy resin compositions for making outdoor articles and articles obtained therefrom 亨斯迈先进材料许可(瑞士)有限公司 2021-12-10 CN disclosed
CN-109074899-B Epoxy-based electrical insulation system for generators and motors 亨斯迈先进化工材料许可(瑞士)有限公司 2021-03-16 CN disclosed
EP-3430629-B1 ELECTRICAL INSULATION SYSTEM BASED ON EPOXY RESINS FOR GENERATORS AND MOTORS HUNTSMAN ADV MAT LICENSING SWITZERLAND GMBH (CH) 2020-03-18 EP disclosed
US-20190080818-A1 Electrical Insulation System Based on Epoxy Resins for Generators and Motors HUNSTMAN ADVANCED MATERIALS LICENSING (SWITZERLAND) GMBH (CH) 2019-03-14 US disclosed
EP-3430629-A1 ELECTRICAL INSULATION SYSTEM BASED ON EPOXY RESINS FOR GENERATORS AND MOTORS Huntsman Advanced Materials Licensing (Switzerland) GmbH (CH) 2019-01-23 EP disclosed
US-20180371153-A1 A Thermosetting Epoxy Resin Composition for the Preparation of Outdoor Articles, and the Articles Obtained Therefrom HUNTSMAN INTERNATIONAL LLC 2018-12-27 US disclosed
CN-109074899-A The electrical insulation system based on epoxy resin for generator and motor 亨斯迈先进化工材料许可(瑞士)有限公司 2018-12-21 CN disclosed
CN-108026248-A It is used to prepare the thermosetting epoxy resin composition of outdoor product and thus obtained product 亨斯迈先进材料许可(瑞士)有限公司 2018-05-11 CN disclosed
EP-3317318-A1 A THERMOSETTING EPOXY RESIN COMPOSITION FOR THE PREPARATION OF OUTDOOR ARTICLES, AND THE ARTICLES OBTAINED THEREFROM Huntsman Advanced Materials Licensing (Switzerland) GmbH (CH) 2018-05-09 EP disclosed
WO-2017001182-A1 A THERMOSETTING EPOXY RESIN COMPOSITION FOR THE PREPARATION OF OUTDOOR ARTICLES, AND THE ARTICLES OBTAINED THEREFROM HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2017-01-05 WO disclosed
US-6579566-B1 Heating wire coils in ovens, then applying protective coatings comprising polyepoxides having impact strength and flexibility VANTICO INC. 2003-06-17 US disclosed
EP-0996506-B1 METHOD FOR THE COATING OR ENCAPSULATION OF FLUIDISABLE SUBSTRATES VANTICO AG (CH) 2002-08-14 EP disclosed
US-6093493-A Method for the coating or encapsulation of fluidizable substrates CIBA SPECIALTY CHEMICALS CORP. (US) 2000-07-25 US disclosed
EP-0996506-A1 METHOD FOR THE COATING OR ENCAPSULATION OF FLUIDISABLE SUBSTRATES Ciba SC Holding AG (CH) 2000-05-03 EP disclosed
WO-1999001231-A1 METHOD FOR THE COATING OR ENCAPSULATION OF FLUIDISABLE SUBSTRATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-01-14 WO disclosed
US-4393185-A EPOXIDES CIBA-GEIGY CORPORATION (US) 1983-07-12 US disclosed
US-4220742-A Process for the polymerization of ethylene in the presence of diaryl glycol ethers BAYER AKTIENGESELLSCHAFT (DE) 1980-09-02 US disclosed