Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6460719 | 1.00 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AGPR84 | |
| SCHEMBL5741494 | 1.00 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AGPR84 | |
| SCHEMBL6462902 | 1.00 | KDM4C (0.43) | KDM4CKDM4APHF8KDM2AGPR84 | |
| SCHEMBL6465236 | 0.98 | BLM (0.41) | KDM4CKDM4APHF8KDM2AGPR84 | |
| SCHEMBL6460876 | 0.94 | BLM (0.45) | KDM4CKDM4APHF8KDM2AGPR84 | |
| SCHEMBL9620654 | 0.89 | GPR84 (0.45) | GPR84LMNAFFAR4FFAR1 | |
| SCHEMBL6466477 | 0.85 | CACNA2D1 (0.39) | BLMCACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL6466759 | 0.83 | GPR84 (0.62) | GPR84FFAR4FFAR1 | |
| SCHEMBL28499460 | 0.83 | GPR84 (0.62) | GPR84FFAR4FFAR1 | |
| SCHEMBL29894891 | 0.83 | GPR84 (0.62) | GPR84FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344763-A1 | Process for producing optically active 3-halogenocarboxylic acid esters and 3-azide-carboxylic acid esters | Takasago International Corporation (JP) | 2003-09-17 | — | — | EP | disclosed |