Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7176646 | 1.00 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7178203 | 1.00 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7177476 | 1.00 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7173233 | 1.00 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7177548 | 1.00 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7175528 | 1.00 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7172205 | 0.99 | TP53 (0.66) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7181263 | 0.97 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7173543 | 0.97 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT | |
| Hydrochloric Acid SCHEMBL7176268 | 0.97 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |