Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monothioglycerol SCHEMBL4463 | 1.00 | — | — | |
| Monothioglycerol SCHEMBL4462 | 1.00 | — | — | |
| Monothioglycerol SCHEMBL3444091 | 1.00 | — | — | |
| Monothioglycerol SCHEMBL1550845 | 0.96 | — | — | |
| Monothioglycerol SCHEMBL6655505 | 0.96 | LMNA (0.93) | LMNAALDH1A1TDP1NR1I2CYP1A2 | |
| Monothioglycerol SCHEMBL9773241 | 0.96 | — | — | |
| Glycerin SCHEMBL9866655 | 0.96 | LMNA (0.93) | LMNAALDH1A1TDP1NR1I2CYP1A2 | |
| Monothioglycerol SCHEMBL1551087 | 0.96 | — | — | |
| Monothioglycerol SCHEMBL5973538 | 0.96 | — | — | |
| Monothioglycerol SCHEMBL1997953 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716393-B2 | Functionalized polysulfide silica coupling agents and silica reinforced rubber composition for tire components | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-06 | — | — | US | claimed |
| US-20120053300-A1 | FUNCTIONALIZED POLYSULFIDE SILICA COUPLING AGENTS AND SILICA REINFORCED RUBBER COMPOSITION FOR TIRE COMPONENTS | GOODYEAR TIRE & RUBBER COMPANY, THE | 2012-03-01 | — | — | US | claimed |
| EP-1191058-B1 | Silica reinforced rubber composition which contains thioglycerol coupling agent and benzothiazyl disulfide and article of manufacture | GOODYEAR TIRE & RUBBER (US) | 2005-08-17 | — | — | EP | claimed |
| EP-3863591-A1 | COLD SOLUTION FOR FAT REDUCTION | Miraki Innovation Think Tank, LLC (US) | 2021-08-18 | — | — | EP | disclosed |
| WO-2018118962-A1 | FLUORINATED ANIONIC POLYMERS AND COMPOSITIONS INCLUDING THEM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-06-28 | — | — | WO | disclosed |
| CN-105611932-A | Injection preparation and process for producing the same | FUJIFILM CORP | 2016-05-25 | — | — | CN | disclosed |
| CN-102209541-B | Modulators of aldehyde dehydrogenase activity and its using method | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-05-18 | — | — | CN | disclosed |
| US-20150274862-A1 | METHOD FOR CONVERTING REACTIVE GROUPS OF SI-C-BOUND GROUPS OF SILANES WHILE SIMULTANEOUSLY INCREASING THE PHYSICAL DISTANCE BETWEEN SAID GROUPS | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2015-10-01 | — | — | US | disclosed |
| US-8716393-B2 | Functionalized polysulfide silica coupling agents and silica reinforced rubber composition for tire components | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-06 | — | — | US | disclosed |
| EP-1136507-B1 | Cement dispersing polymers for high flow, high strength and selfcompacting concrete | SIKA TECHNOLOGY AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| US-20120053300-A1 | FUNCTIONALIZED POLYSULFIDE SILICA COUPLING AGENTS AND SILICA REINFORCED RUBBER COMPOSITION FOR TIRE COMPONENTS | GOODYEAR TIRE & RUBBER COMPANY, THE | 2012-03-01 | — | — | US | disclosed |
| EP-1136507-A1 | Cement dispersing polymers for high flow, high strength and selfcompacting concrete | Sika AG, vorm. Kaspar Winkler & Co. (CH) | 2001-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274862-A1 | METHOD FOR CONVERTING REACTIVE GROUPS OF SI-C-BOUND GROUPS OF SILANES WHILE SIMULTANEOUSLY INCREASING THE PHYSICAL DISTANCE BETWEEN SAID GROUPS | NR4A1, NR4A3, NR3C2 | LMNA 1369/4885ALDH1A1 2664/4885TDP1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.