Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7183697 | 0.99 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7171289 | 0.99 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7176539 | 0.99 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7180447 | 0.99 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7179477 | 0.99 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7177564 | 0.99 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7176747 | 0.99 | TP53 (0.64) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7172205 | 0.97 | TP53 (0.66) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7173259 | 0.97 | TP53 (0.66) | TP53TLR8SMN1; SMN2GAAHTT | |
| Hydrochloric Acid SCHEMBL7183425 | 0.97 | TP53 (0.66) | TP53TLR8SMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |