Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 17/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062089 | 0.93 | CTSS (0.43) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7046914 | 0.86 | CTSS (0.36) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7043352 | 0.85 | DAGLA (0.39) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7182998 | 0.82 | CTSS (0.52) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL7048614 | 0.80 | DAGLA (0.41) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7183163 | 0.80 | CTSS (0.43) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6463860 | 0.80 | CTSS (0.43) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7049518 | 0.79 | DAGLA (0.46) | FAAHCES1DAGLA | |
| SCHEMBL6465501 | 0.77 | LONP1 (0.43) | FAAHCES1DAGLACTSL | |
| SCHEMBL6464114 | 0.76 | CTSS (0.61) | CTSSCTSLCTSBCTSKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |