Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 6/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL9550812 | 0.94 | PRSS1 (0.62) | ACRPRSS1KMT2AMEN1MAPT | |
| SCHEMBL29210105 | 0.94 | ACR (0.62) | ACRPRSS1KMT2AMEN1MAPT | |
| SCHEMBL25491843 | 0.87 | MAPT (0.58) | ACRPRSS1KMT2AMEN1MAPT | |
| SCHEMBL9726291 | 0.85 | ACR (0.61) | ACRPRSS1KMT2AMAPTKDM4E | |
| SCHEMBL9726260 | 0.84 | STS (0.57) | ACRPRSS1KMT2AMEN1MAPT | |
| SCHEMBL9663961 | 0.84 | PRSS1 (0.69) | ACRPRSS1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2741098 | 0.84 | PRSS1 (0.69) | ACRPRSS1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8929987 | 0.84 | PRSS1 (0.69) | ACRPRSS1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1101878 | 0.84 | PRSS1 (0.69) | ACRPRSS1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8930157 | 0.84 | PRSS1 (0.69) | ACRPRSS1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083167-B1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEM CO (US) | 2003-04-16 | — | — | EP | disclosed |
| US-6448430-B1 | BY REACTION OF A PHENOL WITH A CARBOXYLIC ACID IN THE PRESENCE OF TRIFLUOROACETIC ACID (TFA) AND TRIFLUOROACETIC ANHYDRIDE (TFAA); RELATIVELY LOW TEMPERATURE | EASTMAN CHEMICAL COMPANY | 2002-09-10 | — | — | US | disclosed |
| EP-1083167-A1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |