Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242451 | 0.88 | NCF1 (0.45) | ALDH1A1KDM4EGAANCF1SLC6A4 | |
| SCHEMBL1206785 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EGAASLC6A4SLC6A2 | |
| SCHEMBL31069432 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EGAASLC6A4SLC6A2 | |
| SCHEMBL6187977 | 0.80 | KDM4E (0.51) | ALDH1A1KDM4EGAAKAT2BPRSS1 | |
| SCHEMBL29519346 | 0.80 | KDM4E (0.51) | ALDH1A1KDM4EGAAKAT2BPRSS1 | |
| SCHEMBL2083380 | 0.79 | KDM4E (0.54) | ALDH1A1KDM4EGAASLC6A4SLC6A2 | |
| SCHEMBL15585982 | 0.79 | NCF1 (0.47) | ALDH1A1NCF1NPSR1SLC2A1HRH3 | |
| SCHEMBL24320215 | 0.79 | PTGER4 (0.56) | ALDH1A1KDM4EGAANCF1EGLN2 | |
| SCHEMBL2866192 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4EGAASLC6A4SLC6A2 | |
| SCHEMBL11720142 | 0.78 | HDAC6 (0.55) | ALDH1A1NCF1SLC6A4NPSR1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |