Methacrylic Acid

Methacrylic Acid

SCHEMBL7183113

C=C(C)C(=O)O.C=C(C)C(=O)OC(F)(F)c1ccccc1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
KCNN4 O15554 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
PTPN1 P18031 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 6/20 0.34
CES1 P23141 3/20 0.34
KDM4E B2RXH2 3/20 0.34
CES2 O00748 1/20 0.34
ACHE P22303 1/20 0.34
BACE1 P56817 1/20 0.33
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HDAC3 O15379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633823 0.97 ELANE (0.42) ELANEKCNN4CYP2C19HIF1APTPN1
SCHEMBL14648216 0.83 ELANE (0.42) ELANEKCNN4CYP2C19HIF1APTPN1
Methacrylic Acid SCHEMBL27752618 0.83 ELANE (0.42) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL27496577 0.83 CYP2C19 (0.43) ELANEKCNN4CYP2C19HIF1APTPN1
SCHEMBL3692621 0.80 ELANE (0.41) ELANEKCNN4CYP2C19HIF1APTPN1
SCHEMBL435821 0.79 ELANE (0.45) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL3180129 0.79 CYP2C19 (0.46) ELANEKCNN4CYP2C19HIF1ACYP1A2
SCHEMBL15836528 0.79 ELANE (0.40) ELANEKCNN4CYP2C19HIF1APTPN1
Trifluoromethylbenzene SCHEMBL28603020 0.78 ALDH1A1 (0.58) PTPN1MAPTKMT2AALDH1A1CES1
SCHEMBL25840105 0.78 CYP2C19 (0.44) ELANEKCNN4CYP2C19HIF1APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0878503-B1 RUBBER COMPOSITION LOWERED IN HEAT BUILD-UP AND ROLLS NIPPON ZEON CO (JP) 2003-12-17 EP disclosed
EP-0878503-A1 RUBBER COMPOSITION LOWERED IN HEAT BUILD-UP AND ROLLS NIPPON ZEON CO., LTD. (JP) 1998-11-18 EP disclosed