2,4-Dichlorophenoxyacetic Acid

2,4-Dichlorophenoxyacetic Acid

SCHEMBL7183365

C=C(C)C(=O)[O-].O=C([O-])COc1ccc(Cl)cc1Cl.[Cu+2]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.57
TSHR P16473 2/20 0.56
SMN1; SMN2 Q16637 3/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 2/20 0.49
POLB P06746 1/20 0.49
HTT P42858 1/20 0.49
ADRB2 P07550 1/20 0.48
MAPT P10636 2/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
PPARD Q03181 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenoxyacetic Acid SCHEMBL7177988 0.97 TDP1 (0.57) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL7177954 0.97 TDP1 (0.57) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL1623675 0.93 TDP1 (0.60) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL1624187 0.90 TDP1 (0.60) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL1623004 0.90 TDP1 (0.60) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL4588342 0.90 TDP1 (0.70) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL166226 0.90 TDP1 (0.70) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL29385304 0.90 TDP1 (0.70) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL13571537 0.87 TDP1 (0.70) TDP1TSHRSMN1; SMN2MEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL2400880 0.87 TDP1 (0.70) TDP1TSHRSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6630079-B2 Bis(2- pyridinethiol-1-oxide) copper salt, does not exert any adverse influence on the storage stability or antifouling effect, and the effect of the salt does not change by the coating with an acrylic resin API CORPORATION (JP) 2003-10-07 US disclosed
EP-1080640-B1 COATED BIS(2-PYRIDINETHIOL-1-OXIDE)COPPER SALT API CORP (JP) 2003-09-10 EP disclosed
US-20030124085-A1 Coated bis (2-pyridinethiol-1-oxide) copper salt API CORPORATION (JP) 2003-07-03 US disclosed
US-6544440-B1 Antifouling active ingredient for a coating for the bottom of a ship, which is safe during handling; rosin coated; biocides API CORPORATION (JP) 2003-04-08 US disclosed
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
EP-1080640-A1 COATED BIS(2-PYRIDINETHIOL 1-OXIDE) COPPER SALT Yoshitomi Fine Chemicals, Ltd. (JP) 2001-03-07 EP disclosed