Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of 2,4-Dichlorophenoxyacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL29385304 | 1.00 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL583961 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL28782052 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL29364305 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4586667 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4588342 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4587469 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL2400880 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL13571537 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL28782085 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024041926-A1 | HERBICIDAL COMPOSITIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-02-29 | — | — | WO | claimed |
| WO-2023003765-A1 | COMPOSITIONS WITH MICROENCAPSULATED ACETAMIDE AND METAL-CHELATED MESOTRIONE | MONSANTO TECHNOLOGY LLC (US) | 2023-01-26 | — | — | WO | claimed |
| US-20230000079-A1 | COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION | Generic Crop Science LLC (US) | 2023-01-05 | — | — | US | claimed |
| CN-110461158-B | Herbicidal mixtures comprising 2- [ (2, 4-dichlorophenyl) methyl ] -4, 4-dimethyl-3-isoxazolidone, topramezone and mefenpyr | 拜耳公司 | 2021-12-10 | — | — | CN | claimed |
| US-20210378241-A1 | COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION | Generic Crop Science LLC (US) | 2021-12-09 | — | — | US | claimed |
| CN-110461157-B | Herbicidal mixtures | 拜耳公司 | 2021-11-02 | — | — | CN | claimed |
| CN-110087467-B | Herbicidal combination | 拜耳作物科学股份公司 | 2021-08-13 | — | — | CN | claimed |
| CN-112469277-A | Herbicidal mixtures comprising aclonifen and cinmethylin | 拜耳公司 | 2021-03-09 | — | — | CN | claimed |
| EP-3174865-B1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-12-09 | — | — | EP | claimed |
| CN-111903705-A | Compound herbicide and application thereof | 浙江瑞丰生物科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | claimed |
| WO-2012061288-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | claimed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | claimed |
| US-20120110701-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-03 | — | — | US | claimed |
| CN-1173627-C | Light, extruded compositions containing a light, extrudable, ceramic carrier, methods for their use, and processes for their preparation | �����ɷ� | 2004-11-03 | — | — | CN | claimed |
| EP-1150562-B1 | LIGHT, EXTRUDED COMPOSITIONS CONTAINING A LIGHT, EXTRUDABLE, CERAMIC CARRIER, METHODS FOR THEIR USE, AND PROCESSES FOR THEIR PREPARATION | BASF AG (DE) | 2004-04-28 | — | — | EP | claimed |
| CN-1339945-A | Lightweight extrudable composition containing lightweight extrudable ceramic carrier, method of use and method of making same | BASF AG (DE) | 2002-03-13 | — | — | CN | claimed |
| US-6340656-B1 | FOR APPLYING AGRICULTURAL COMPOUND TO THE WATER OF PADDY FIELDS | AMERICAN CYANAMID CO. | 2002-01-22 | — | — | US | claimed |
| EP-1150562-A1 | LIGHT, EXTRUDED COMPOSITIONS CONTAINING A LIGHT, EXTRUDABLE, CERAMIC CARRIER, METHODS FOR THEIR USE, AND PROCESSES FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000047044-A1 | LIGHT, EXTRUDED COMPOSITIONS CONTAINING A LIGHT, EXTRUDABLE, CERAMIC CARRIER, METHODS FOR THEIR USE, AND PROCESSES FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 2000-08-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000079-A1 | COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION | DDT, TDO2, DNTT | TDP1 289/4885TSHR 3040/4885SMN1; SMN2 3093/4885 |
| US-20210378241-A1 | COMBINATION COMPRISING A BENZAMIDE HERBICIDE AND A PYRIDINE CARBOXYLIC ACID HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION | DDT, GAP43, PDHA2 | TDP1 750/4885TSHR 1921/4885SMN1; SMN2 450/4885 |
| US-20120110701-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, AGPS, DDT | TDP1 2045/4885TSHR 1004/4885SMN1; SMN2 4405/4885 |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | ACHE, DDT, PTMS | TDP1 2067/4885TSHR 1156/4885SMN1; SMN2 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.