Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183457 | 1.00 | HCAR3 (0.52) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL8248585 | 0.92 | HCAR3 (0.59) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL20333669 | 0.87 | KMT2A (0.63) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7187372 | 0.87 | MEN1 (0.67) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7185959 | 0.86 | HCAR3 (0.56) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7185961 | 0.86 | HCAR3 (0.56) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7179398 | 0.86 | HCAR3 (0.53) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7179403 | 0.86 | HCAR3 (0.53) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL7182042 | 0.86 | MEN1 (0.65) | HCAR3KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL4122997 | 0.86 | MEN1 (0.65) | HCAR3KMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |