SCHEMBL7183641

SCHEMBL7183641

O=c1ccn([C@@H]2O[C@H](COC3O[C@@H](CO)[C@H](O)[C@H]3O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.78

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.78
SLC28A2 O43868 1/20 0.78
SLC29A1 Q99808 1/20 0.78
SLC28A3 Q9HAS3 1/20 0.78
P2RY2 P41231 10/20 0.68
P2RY6 Q15077 8/20 0.68
P2RY14 Q15391 7/20 0.68
P2RY4 P51582 5/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1801783 1.00 SLC28A1 (0.78) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5494169 1.00 SLC28A1 (0.78) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL7189865 1.00 SLC28A1 (0.78) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL7573342 0.99 SLC28A1 (0.76) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL7575088 0.93 SLC28A1 (0.67) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4956688 0.93 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL6464709 0.90 SLC28A1 (0.62) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4211565 0.90 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL30019440 0.88 SLC28A1 (0.95) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2912983 0.88 SLC28A1 (1.00) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1327637-A1 Process for the preparation of L-Ribose UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2003-07-16 EP disclosed
EP-0998482-A1 PROCESS FOR THE PREPARATION OF 2'-FLUORO-5-METHYL-$g(b) -L-ARABINOFURANOSYLURIDINE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2000-05-10 EP disclosed
WO-1999005158-A1 PROCESS FOR THE PREPARATION OF 2'-FLUORO-5-METHYL-β -L-ARABINOFURANOSYLURIDINE THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1999-02-04 WO disclosed