Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7191463 | 0.90 | ESR1 (0.54) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7188067 | 0.90 | CA12 (0.56) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7193933 | 0.88 | ESR1 (0.54) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7186125 | 0.87 | ESR1 (0.54) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7191281 | 0.87 | ESR1 (0.66) | ESR1ESR2 | |
| SCHEMBL7191284 | 0.87 | ESR1 (0.66) | ESR1ESR2 | |
| SCHEMBL7182779 | 0.86 | ESR1 (0.52) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7189145 | 0.84 | CYP3A4 (0.52) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7189095 | 0.83 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL7194195 | 0.82 | ESR1 (0.49) | ESR1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |