Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369029 | 0.84 | LSS (0.55) | LSSMEN1KMT2A | |
| SCHEMBL3363347 | 0.79 | LSS (0.57) | LSSMEN1KMT2A | |
| SCHEMBL3368283 | 0.77 | LSS (0.56) | LSSMEN1KMT2A | |
| SCHEMBL3366117 | 0.76 | LSS (0.55) | LSSMEN1KMT2A | |
| SCHEMBL6405900 | 0.76 | LSS (0.46) | LSSMEN1KMT2A | |
| SCHEMBL6397866 | 0.76 | LSS (0.46) | LSSMEN1KMT2A | |
| SCHEMBL6403997 | 0.76 | LSS (0.46) | LSSMEN1KMT2A | |
| SCHEMBL7165672 | 0.75 | LSS (0.49) | LSS | |
| SCHEMBL3397097 | 0.72 | LSS (0.51) | LSS | |
| SCHEMBL4808866 | 0.72 | LSS (0.51) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303503-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006189-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |