Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 15/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599410 | 0.92 | OPRD1 (0.69) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7184052 | 0.89 | OPRD1 (0.57) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7184049 | 0.85 | OPRD1 (0.53) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6599241 | 0.83 | OPRD1 (0.54) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7184062 | 0.82 | OPRD1 (0.50) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6601930 | 0.81 | OPRD1 (0.53) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7196680 | 0.80 | OPRD1 (0.49) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6599707 | 0.78 | OPRD1 (0.57) | OPRD1OPRK1OPRM1 | |
| SCHEMBL6602363 | 0.78 | OPRD1 (0.67) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7196676 | 0.77 | OPRD1 (0.48) | OPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586431-B1 | Treating drug abuse and drug dependence; nervous system and gastrointestinal disorders | PFIZER INC | 2003-07-01 | — | — | US | disclosed |