Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184528 | 0.90 | PBRM1 (0.42) | PBRM1LMNAHTTRAB9AMAPT | |
| SCHEMBL11872265 | 0.87 | PBRM1 (0.61) | PBRM1LMNAHTTRAB9AHPGD | |
| SCHEMBL27147137 | 0.86 | PBRM1 (0.52) | PBRM1CA12CA1CA2CA9 | |
| SCHEMBL7183509 | 0.82 | NPC1 (0.41) | PBRM1CA12CA1CA2CA9 | |
| SCHEMBL7192032 | 0.81 | PBRM1 (0.65) | PBRM1CA1CA2CA9LMNA | |
| SCHEMBL8809313 | 0.81 | MAPK1 (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7940092 | 0.81 | CA12 (0.53) | PBRM1CA12CA1CA2CA9 | |
| SCHEMBL29088630 | 0.79 | PARP1 (0.58) | PBRM1CA1CA2CA9LMNA | |
| SCHEMBL7190432 | 0.79 | MAPT (0.39) | PBRM1HTTHPGDMAPTMAPK1 | |
| SCHEMBL9097535 | 0.78 | CA12 (0.59) | PBRM1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |