SCHEMBL7184528

SCHEMBL7184528

Nc1cc(Br)cc(C(=O)c2cc(N)cc(Br)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.42
PARP1 P09874 1/20 0.39
MAPT P10636 4/20 0.37
POLB P06746 3/20 0.37
HTT P42858 3/20 0.37
ALOX15 P16050 1/20 0.37
KDM4E B2RXH2 3/20 0.36
CTSL P07711 2/20 0.36
NPC1 O15118 3/20 0.36
LMNA P02545 3/20 0.36
RAB9A P51151 2/20 0.36
USP2 O75604 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MITF O75030 1/20 0.36
GAA P10253 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7184429 0.90 PBRM1 (0.44) PBRM1MAPTPOLBHTTALOX15
SCHEMBL11872265 0.88 PBRM1 (0.61) PBRM1PARP1MAPTPOLBHTT
SCHEMBL7192032 0.87 PBRM1 (0.65) PBRM1PARP1MAPTPOLBHTT
SCHEMBL30197207 0.84 KDM4E (0.47) PBRM1PARP1MAPTPOLBALOX15
SCHEMBL1028516 0.84 KDM4E (0.47) PBRM1PARP1MAPTPOLBALOX15
SCHEMBL15484864 0.84 PARP1 (0.52) PARP1MAPTPOLBHTTKDM4E
SCHEMBL7183509 0.84 NPC1 (0.41) PBRM1MAPTPOLBHTTKDM4E
SCHEMBL17635528 0.82 CA5A (0.43) PARP1MAPTHTTKDM4ENPC1
SCHEMBL1168105 0.82 HTT (0.43) PARP1MAPTPOLBHTTALOX15
SCHEMBL8196675 0.82 PBRM1 (0.50) PBRM1MAPTPOLBHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286359-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2022-03-29 US disclosed
US-11111345-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2021-09-07 US disclosed
US-20170327657-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2017-11-16 US disclosed
US-9765194-B2 Prepreg and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2017-09-19 US disclosed
EP-2878617-B1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2017-03-01 EP disclosed
US-20150210813-A1 PREPREG AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2015-07-30 US disclosed
EP-2878617-A1 PREPREG AND CARBON-FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2015-06-03 EP disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed