Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.48 |
| ▸ | P4HB | P07237 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180114 | 0.93 | ABCG2 (0.62) | ABCG2MAOBLMNASMN1; SMN2P4HB | |
| SCHEMBL7184728 | 0.88 | ABCG2 (0.56) | ABCG2MAOBBCHELMNASMN1; SMN2 | |
| SCHEMBL7184176 | 0.88 | ABCG2 (0.61) | ABCG2MAOBLMNASMN1; SMN2P4HB | |
| SCHEMBL7184186 | 0.88 | ABCG2 (0.61) | ABCG2MAOBLMNASMN1; SMN2P4HB | |
| SCHEMBL7190647 | 0.86 | ABCG2 (0.53) | ABCG2MAOBBCHELMNASMN1; SMN2 | |
| SCHEMBL7192480 | 0.86 | ABCG2 (0.53) | ABCG2BCHELMNASMN1; SMN2ACHE | |
| SCHEMBL7191650 | 0.86 | ABCG2 (0.51) | ABCG2MAOBBCHELMNASMN1; SMN2 | |
| SCHEMBL7186152 | 0.85 | ABCG2 (0.59) | ABCG2MAOBBCHELMNASMN1; SMN2 | |
| SCHEMBL7186727 | 0.84 | ABCG2 (0.52) | ABCG2MAOBBCHEDPP4PTPN1 | |
| SCHEMBL7185283 | 0.84 | ABCG2 (0.51) | ABCG2MAOBBCHELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |