Ethylene

Ethylene

SCHEMBL7184477

C=C.C=C(CCO)C(=O)O

nearest known ligand 0.46

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.39
TET3 O43151 1/20 0.39
TET1 Q8NFU7 1/20 0.39
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
GRM1 Q13255 1/20 0.37
GRM2 Q14416 1/20 0.37
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CAMK2A Q9UQM7 1/20 0.35
TBXAS1 P24557 2/20 0.32
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
OR51E2 Q9H255 1/20 0.32
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16661 0.97
SCHEMBL7758820 0.97 TET2 (0.40) TET2TET3TET1GRIK1GRIK2
SCHEMBL29150247 0.94
SCHEMBL30849720 0.94
SCHEMBL4532573 0.94 TET2 (0.39) TET2TET3TET1GRIK1GRIK2
SCHEMBL5698428 0.92 GRIK1 (0.41) TET2TET3TET1GRIK1GRIK2
Urea SCHEMBL29140399 0.89 GRIK1 (0.39) TET2TET3TET1GRIK1GRIK2
SCHEMBL1627003 0.89 TET2 (0.36) TET2TET3TET1GRIK1GRIK2
SCHEMBL9340610 0.89 TET2 (0.36) TET2TET3TET1GRIK1GRIK2
Succinic Acid SCHEMBL2484910 0.89 LMNA (0.47) TET2TET3TET1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827995-B1 Hot melt adhesives comprising low free monomer, low oligomer content isocyanate prepolymers AIR PROD & CHEM (US) 2003-11-12 EP disclosed
US-6280561-B1 Hot melt adhesives comprising low free monomer, low oligomer isocyanate prepolymers AIR PRODUCTS AND CHEMICALS, INC. 2001-08-28 US disclosed
EP-0827995-A2 Hot melt adhesives comprising low free monomer, low oligomer content isocyanate prepolymers AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-03-11 EP disclosed
EP-0092446-B1 THERMALLY CURABLE OLEFINIC POLYMERS AND MANUFACTURING METHOD FOR CURED SHAPED OBJECTS MADE THEREOF ELF ATOCHEM S.A. (FR) 1987-12-16 EP disclosed
EP-0092446-A1 Thermally curable olefinic polymers and manufacturing method for cured shaped objects made thereof ELF ATOCHEM S.A. (FR) 1983-10-26 EP disclosed