Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186182 | 0.95 | PTPN1 (0.48) | DPP4ABCG2CYP1A1CYP1B1PTPN1 | |
| SCHEMBL7192399 | 0.92 | LMNA (0.46) | DPP4ABCG2CYP1A1CYP1B1PTPN1 | |
| SCHEMBL7192400 | 0.92 | LMNA (0.46) | DPP4ABCG2CYP1A1CYP1B1PTPN1 | |
| SCHEMBL7189251 | 0.89 | PTPN1 (0.52) | PTPN1 | |
| SCHEMBL7188883 | 0.88 | ABCG2 (0.55) | DPP4ABCG2CYP1A1CYP1B1PTPN1 | |
| SCHEMBL9114110 | 0.88 | DPP4 (0.59) | DPP4ABCG2CYP1A1CYP1B1PTPN1 | |
| SCHEMBL7190705 | 0.87 | DPP4 (0.47) | DPP4ABCG2CYP1A1CYP1B1PTPN1 | |
| SCHEMBL7180253 | 0.87 | ABCG2 (0.59) | DPP4ABCG2PTPN1CAPN1 | |
| SCHEMBL7180245 | 0.87 | ABCG2 (0.59) | DPP4ABCG2PTPN1CAPN1 | |
| SCHEMBL7192579 | 0.87 | DPP4 (0.47) | DPP4ABCG2CYP1A1CYP1B1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |