Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046902 | 0.95 | HSP90AA1 (0.40) | HSP90AA1PTGER4PRSS1PRSS2PRSS3 | |
| SCHEMBL7045972 | 0.93 | TP53 (0.38) | HSP90AA1PTGER4MAPTMEN1KMT2A | |
| SCHEMBL7046400 | 0.89 | PTGER4 (0.38) | PTGER4MAPTFOLH1HDAC3HDAC4 | |
| SCHEMBL7049411 | 0.85 | TLR2 (0.38) | PTGER4MAPTFOLH1 | |
| SCHEMBL7042861 | 0.84 | FOLH1 (0.36) | PTGER4MAPTFOLH1BMP1HTT | |
| SCHEMBL7049142 | 0.83 | ANPEP (0.37) | PTGER4MAPTFOLH1HDAC3HDAC4 | |
| SCHEMBL7042122 | 0.82 | FOLH1 (0.35) | PTGER4MAPTFOLH1HDAC1HDAC6 | |
| SCHEMBL7046323 | 0.78 | HDAC1 (0.44) | PTGER4MAPTFOLH1HDAC3HDAC4 | |
| SCHEMBL6061842 | 0.73 | MAPT (0.38) | HSP90AA1PTGER4MAPTL3MBTL1FOLH1 | |
| SCHEMBL6062759 | 0.72 | PSMB1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |