Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124348 | 1.00 | HSD11B1 (0.49) | HSD11B1PIK3CDUSP30BTKSYK | |
| SCHEMBL31170927 | 1.00 | HSD11B1 (0.49) | HSD11B1PIK3CDUSP30BTKSYK | |
| SCHEMBL7185231 | 1.00 | HSD11B1 (0.49) | HSD11B1PIK3CDUSP30BTKSYK | |
| SCHEMBL29124443 | 0.88 | HSD11B1 (0.51) | HSD11B1PIK3CDUSP30BTKGPR119 | |
| SCHEMBL31170926 | 0.88 | HSD11B1 (0.51) | HSD11B1PIK3CDUSP30BTKGPR119 | |
| SCHEMBL29124441 | 0.88 | HSD11B1 (0.51) | HSD11B1PIK3CDUSP30BTKGPR119 | |
| SCHEMBL2636954 | 0.87 | HSD11B1 (0.63) | HSD11B1PIK3CDUSP30BTKGPR119 | |
| SCHEMBL2636953 | 0.87 | HSD11B1 (0.63) | HSD11B1PIK3CDUSP30BTKGPR119 | |
| SCHEMBL23236169 | 0.86 | HSD11B1 (0.49) | HSD11B1PIK3CDPIK3CAMAPTTDP1 | |
| SCHEMBL23236166 | 0.86 | HSD11B1 (0.49) | HSD11B1PIK3CDPIK3CAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689637-B | Imidazopyridone compounds | 橘生药品工业株式会社 | 2023-11-10 | — | — | CN | disclosed |
| US-6582351-B1 | Benzimidazole heterocyclic compounds having pharmacological activities, and their use as a medicament for treatment or prevention of diseases mediated by cGMP-PDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |