Sugi Predict

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SCHEMBL7185576

SCHEMBL7185576

Cc1cc(C)c(C(=O)c2ccccc2[P](=O)C(C)C)c(C)c1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCL2L1 Q07817 1/20 0.34
▸ CNR2 P34972 9/20 0.33
▸ CNR1 P21554 8/20 0.33
▸ KMT2A Q03164 4/20 0.32
▸ ALDH1A1 P00352 4/20 0.32
▸ MEN1 O00255 3/20 0.32
▸ HPGD P15428 2/20 0.32
▸ NR1I2 O75469 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ NR1H4 Q96RI1 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ CRHBP P24387 1/20 0.32
▸ CRHR2 Q13324 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7188470 0.87 MEN1 (0.31) CNR2CNR1KMT2AALDH1A1MEN1
SCHEMBL7182214 0.86 HPGD (0.42) BCL2L1CNR2CNR1KMT2AALDH1A1
SCHEMBL7180640 0.83 ALDH1A1 (0.34) CNR2CNR1KMT2AALDH1A1MEN1
SCHEMBL7190118 0.82 CNR2 (0.38) BCL2L1CNR2CNR1KMT2AALDH1A1
SCHEMBL7181631 0.82 ALDH1A1 (0.33) BCL2L1KMT2AALDH1A1MEN1HPGD
SCHEMBL7189935 0.82 ALDH1A1 (0.33) CNR2CNR1KMT2AALDH1A1MEN1
SCHEMBL7175729 0.81 ALDH1A1 (0.32) KMT2AALDH1A1MEN1HPGDKDM4E
SCHEMBL7187147 0.80 — —
SCHEMBL7177297 0.78 KMT2A (0.35) BCL2L1KMT2AALDH1A1MEN1HPGD
SCHEMBL7180044 0.78 KMT2A (0.37) BCL2L1KMT2AALDH1A1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 BCL2L1 1400/4885CNR2 1721/4885CNR1 651/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 BCL2L1 1529/4885CNR2 1343/4885CNR1 583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.