SCHEMBL7185696

SCHEMBL7185696

CC1(C)CC(CO)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
KDM4C Q9H3R0 1/20 0.36
HTR2C P28335 1/20 0.36
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
OPRL1 P41146 1/20 0.35
NOTUM Q6P988 2/20 0.35
SIGMAR1 Q99720 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30886993 0.83 HTR2A (0.39) HTR2AKDM4CHTR2CSIGMAR1
SCHEMBL11524465 0.83 HTR2A (0.39) HTR2AKDM4CHTR2CSIGMAR1
SCHEMBL30839578 0.83 HTR2A (0.39) HTR2AKDM4CHTR2CSIGMAR1
SCHEMBL19210033 0.80 CYSLTR2 (0.41) HTR2AKDM4CHTR2CNOTUM
SCHEMBL31326461 0.80 HSD11B1 (0.48) KDM4CGAASMN1; SMN2NOTUM
SCHEMBL10339554 0.80 HSD11B1 (0.48) KDM4CGAASMN1; SMN2NOTUM
SCHEMBL1093178 0.79 HTR2A (0.42) HTR2AKDM4CHTR2CGAASMN1; SMN2
SCHEMBL10339564 0.79 HTR2A (0.39) HTR2AKDM4CHTR2CSIGMAR1
SCHEMBL10389799 0.77 CYSLTR2 (0.51) HTR2AKDM4CHTR2CGAASMN1; SMN2
SCHEMBL10389169 0.76 HTR2A (0.37) HTR2AKDM4CHTR2CGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4968667-A 1,1-dimethyl-3-hydroxymethylindane and perfumery composition comprising the same KAO CORPORATION (JP) 1990-11-06 US claimed
EP-0365015-A2 1,1-Dimethyl-3-hydroxymethylindane and perfumery composition comprising the same Kao Corporation (JP) 1990-04-25 EP claimed
JP-2231445-A None JP disclosed
EP-1022265-B1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH & CIE (CH) 2003-03-26 EP disclosed
US-4968667-A 1,1-dimethyl-3-hydroxymethylindane and perfumery composition comprising the same KAO CORPORATION (JP) 1990-11-06 US disclosed
US-4968667-A 1,1-dimethyl-3-hydroxymethylindane and perfumery composition comprising the same KAO CORPORATION (JP) 1990-11-06 US disclosed
US-4968667-A 1,1-dimethyl-3-hydroxymethylindane and perfumery composition comprising the same KAO CORPORATION (JP) 1990-11-06 US disclosed
EP-0365015-A3 1,1-DIMETHYL-3-HYDROXYMETHYLINDANE AND PERFUMERY COMPOSITION COMPRISING THE SAME Kao Corporation (JP) 1990-09-26 EP disclosed
EP-0365015-A3 1,1-DIMETHYL-3-HYDROXYMETHYLINDANE AND PERFUMERY COMPOSITION COMPRISING THE SAME Kao Corporation (JP) 1990-09-26 EP disclosed
JP-H02231445-A 3-ALKOXYMETHYL-1,1-DIMETHYLINDANE AND PERFUME COMPOSITION CONTAINING SAME KAO CORP 1990-09-13 JP disclosed
EP-0385497-A1 Indane derivative and perfumery composition comprising the same KAO CORPORATION (JP) 1990-09-05 EP disclosed
EP-0365015-A2 1,1-Dimethyl-3-hydroxymethylindane and perfumery composition comprising the same Kao Corporation (JP) 1990-04-25 EP disclosed
EP-0365015-A2 1,1-Dimethyl-3-hydroxymethylindane and perfumery composition comprising the same Kao Corporation (JP) 1990-04-25 EP disclosed
EP-0365015-A2 1,1-Dimethyl-3-hydroxymethylindane and perfumery composition comprising the same Kao Corporation (JP) 1990-04-25 EP disclosed