SCHEMBL7185847

SCHEMBL7185847

CC(C)OC(=O)/C(Cl)=C(\Cl)C(Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
ADRA1A P35348 1/20 0.34
PDE4D Q08499 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30
GAA P10253 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720632 0.81 TSHR (0.48) TSHRADRA1APDE4DMEN1KMT2A
SCHEMBL9720626 0.81 TSHR (0.48) TSHRADRA1APDE4DMEN1KMT2A
SCHEMBL11047895 0.77 TSHR (0.43) TSHRADRA1APDE4DMEN1KMT2A
SCHEMBL10594778 0.75 L3MBTL1 (0.35) TSHR
SCHEMBL7180272 0.75 L3MBTL1 (0.35) TSHR
SCHEMBL9745639 0.71 TSHR (0.39) TSHRADRA1APDE4DHTTMEN1
SCHEMBL9720655 0.71 TSHR (0.39) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL9720662 0.71 TSHR (0.39) TSHRADRA1APDE4DHCAR2GAA
SCHEMBL834672 0.71
SCHEMBL28510361 0.70 TSHR (0.37) TSHRADRA1APDE4DHCAR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030114596-A1 Thermoplastic elastomer composition and ethylene-alpha-olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-06-19 US disclosed
US-6541592-B1 An ethylene- alpha -olefin copolymer (alpha -olefin having 3 to 8 carbon atoms and content from 20-33.7wt %), Moony viscosity ML1+4100 degree C. of from 20-60, tensile stress M100 of 2.5 Mpa; excellent flexability, and processability SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-01 US disclosed
EP-0660024-B1 Resin-coated pipe SUMITOMO CHEMICAL CO (JP) 1997-10-22 EP disclosed
US-5571585-A HAVING EXCELLENT PROCESSABILITY, MECHANICAL STRENGTH, NORMAL AND LOW TEMPERATURE IMPACT RESISTANCE, HEAT RESISTANCE, CHIPPING RESISTANCE AND COATING SURFACE APPEEARANCE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-05 US disclosed
EP-0660024-A1 Resin-coated pipe SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-06-28 EP disclosed