Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | KLK1 | P06870 | 4/20 | 0.48 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185839 | 1.00 | KMT2A (0.49) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL3243407 | 0.84 | PRSS1 (0.54) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL3245015 | 0.83 | PRSS1 (0.53) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL3238646 | 0.83 | PRSS1 (0.53) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL3238704 | 0.83 | PRSS1 (0.56) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL3238801 | 0.83 | PRSS1 (0.53) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL8846583 | 0.83 | PRSS1 (0.49) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| Acetic Acid SCHEMBL8903078 | 0.82 | PRSS1 (0.49) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| Acetic Acid SCHEMBL8904308 | 0.81 | PRSS1 (0.49) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL7179292 | 0.81 | L3MBTL1 (0.48) | KMT2AKDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583177-B2 | Amidinophenol derivatives as leukotriene B4 (LTB4)antagonists, phospholipase A2 inhibitors, and trypsin inhibitors. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | claimed |