Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188421 | 0.93 | ESR1 (0.42) | ESR1ESR2MAOBEGFRERBB2 | |
| SCHEMBL7189521 | 0.89 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL7181203 | 0.88 | ESR1 (0.48) | ESR1ESR2HDAC8KDM4ENPC1 | |
| SCHEMBL7181194 | 0.88 | ESR1 (0.48) | ESR1ESR2HDAC8KDM4ENPC1 | |
| SCHEMBL7189126 | 0.87 | ESR1 (0.46) | ESR1ESR2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7190006 | 0.87 | ESR1 (0.49) | ESR1ESR2HDAC8ADORA3MAOB | |
| SCHEMBL7190003 | 0.87 | ESR1 (0.49) | ESR1ESR2HDAC8ADORA3MAOB | |
| SCHEMBL8500327 | 0.84 | ESR1 (0.42) | ESR1ESR2HDAC8BACE1TDP1 | |
| SCHEMBL7181375 | 0.84 | ESR1 (0.50) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL8501042 | 0.84 | ESR1 (0.40) | ESR1ESR2BACE1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |